
Patent Foramen Ovale
What is a patent foramen ovale?
The foramen ovale is a hole between the 2 upper chambers of the heart (the atria).
The heart has 4 sections, or chambers. The upper chambers are each called atria, and the lower chambers are called ventricles. The heart muscle squeezes to push blood through these 4 chambers, to the lungs, and to the rest of the body. Blood flows from the right atrium into the right ventricle, and the right ventricle pumps it to the lungs. As it passes through the lungs, the blood picks up oxygen and leaves behind carbon dioxide. Then the blood flows back to the heart and into the left atrium, and from there into the left ventricle. The left ventricle pumps the blood out to the rest of the body, with a small amount going to the heart muscle itself. The heart pushes blood out through the arteries and blood returns to the heart through the veins.
A foramen ovale is normally present before birth and closes in most children after birth. If the hole does not close all the way, it is called a patent foramen ovale (PFO).
What is the cause?
Before birth, a baby’s blood does not need to go through the lungs to pick up oxygen because the baby gets oxygen-rich blood from the mother. After birth, increased blood pressure on the left side of the heart normally forces a flap over the hole to seal it, so all of the blood then travels from the right side of the heart to the lungs.
Sometimes the flap does not seal. When this happens, the foramen ovale may open at times, and less blood will get to the lungs to pick up oxygen.
It is not known why the flap seals after birth in most people but not everyone.
What are the symptoms?
A PFO usually does not cause any symptoms. In rare cases a baby with PFO may turn blue when crying or straining to pass a bowel movement.
PFO can cause some problems in adults. For example:
- If you have problems with high blood pressure in your lungs, PFO may make shortness of breath much worse.
- Blood clots from another part of the body may pass through the hole and into the brain, which can cause a stroke.
- Migraine headaches are more common in people with PFO.
How is it diagnosed?
Your healthcare provider will ask about your symptoms and medical history and examine you. You may also have an echocardiogram, which uses sound waves (ultrasound) to show pictures of your heart and how well blood is flowing through it.
How is it treated?
Most people with PFO do not need treatment. If you are having surgery for other problems with the heart, the hole may be closed during the surgery.
Your healthcare provider may prescribe blood thinners to lower the chance of blood clots that might cause a stroke.
The hole may need to be closed if your blood needs to get more oxygen from the lungs or to prevent another stroke. This may be done during:
- Heart catheterization (coronary angiogram), which uses a small tube called a catheter inserted into a blood vessel, dye, and X-rays to look at the blood vessels and heart. The healthcare provider will use tools put through the catheter to repair the defect.
- Open heart surgery
How can I take care of myself?
Follow your healthcare provider’s instructions. Ask your provider:
- How and when you will hear your test results
- How long it will take to recover
- If there are activities you should avoid and when you can return to your normal activities
- How to take care of yourself at home
- What symptoms or problems you should watch for and what to do if you have them
Make sure you know when you should come back for a checkup. Keep all of your regular checkup appointments with your healthcare provider.
Patent Foramen Ovale: References
A Hole in the Heart – Patent Foramen Ovale (PFO). National Stroke Association. Accessed July 2014 from http://www.stroke.org/site/PageServer?pagename=PFO
Hara H, Schwartz RS. Patent Foramen Ovale. UpToDate. December 20,2013. Accessed 10/5/2014.
Khositseth, A, Cabalka, AK, Sweeney, JP, et al. Transcatheter Amplatzer device closure of atrial septal defect and patent foramen ovale in patients with presumed paradoxical embolism. Mayo Clin Proc 2004; 79:35.
Meissner, I, Whisnant, JP, Khandheria, BK, et al. Prevalence of potential risk factors for stroke assessed by transesophageal echocardiography and carotid ultrasonography: the SPARC study. Stroke Prevention: Assessment of Risk in a Community. Mayo Clin Proc 1999; 74:862.
Kliegman, Robert M. Nelson Textbook of Pediatrics, 19th Edition. Saunders. 2011.
Pinto, FJ. When and how to diagnose patent foramen ovale. Heart 2005; 91:438.
Schwedt, T. (No date). Patent Foramen Ovale and Migraine. American Headache Society. Retrieved from http://www.americanheadachesociety.org/assets/1/7/Schwedt.pdf.
Wilson, W, Taubert, KA, Gewitz, M, et al. Prevention of Infective Endocarditis. Guidelines From the American Heart Association. A Guideline From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007; 115 published online April 19, 2007.