Anemia of Chronic Disease
What is anemia of chronic disease?
Anemia is a blood problem. It can be either not having enough red blood cells (RBCs), or not having enough hemoglobin (the part of red blood cells that carries oxygen).
If you don’t have enough red blood cells, have too little hemoglobin, or your hemoglobin is not working properly, you can’t get enough oxygen to your cells.
Some chronic (long-term) diseases cause the bone marrow to make fewer red blood cells than normal. Examples of chronic diseases that may cause anemia are:
- Autoimmune diseases, such as lupus and rheumatoid arthritis, that cause your body to attack your own tissue
- Chronic kidney disease
- Chronic liver disease, such as cirrhosis
- Chronic infections, such as hepatitis B or C, a bone infection, or HIV/AIDS
- Cancer
What are the symptoms?
Mild anemia usually does not cause symptoms. With more severe anemia, symptoms may include:
- Feeling unusually weak and tired
- Pale skin and gums
- Lightheadedness or fainting, especially when you stand up
- Fast heartbeat
- Shortness of breath, especially with activity
- Chest pain
How is it diagnosed?
Your healthcare provider will examine you and ask about your symptoms and medical history. You will have blood tests to check for possible causes and to see how serious the anemia is.
What is the treatment?
Your healthcare provider may recommend taking iron and vitamins (like folic acid and B12) if your blood test results show you need them. In some cases your anemia may be cured when the chronic disease is treated.
If the anemia is severe and causes serious symptoms, treatment with blood transfusions can help. You may be given medicine to help your body make more red blood cells.
How can I help take care of myself?
Follow the full course of treatment prescribed by your healthcare provider. Ask your provider:
- How and when you will hear your test results
- How long it will take to recover
- If there are activities you should avoid and when you can return to your normal activities
- How to take care of yourself at home
- What symptoms or problems you should watch for and what to do if you have them
- What vitamins and minerals you should be taking
Make sure you know when you should come back for a checkup.
A healthy lifestyle may also help:
- Eat a healthy diet. Ask your provider about talking to a dietician to create a diet to help with anemia and with your disease.
- Try to keep a healthy weight. If you are overweight, lose weight.
- Stay fit with the right kind of exercise for you, as recommended by your health care provider.
- Limit caffeine if you’re having problems with a fast heartbeat.
- Learn to manage stress. Ask for help at home and work when the load is too great to handle. Find ways to relax, for example take up a hobby, listen to music, watch movies, or take walks. Try deep breathing exercises when you feel stressed.
- If you smoke, try to quit. Talk to your healthcare provider about ways to quit smoking.
- If you want to drink alcohol, ask your healthcare provider how much is safe for you to drink.
- Try to get at least 7 to 9 hours of sleep each night.
Keep all appointments for provider visits or tests. Contact your healthcare provider if you have new or worsening symptoms.
Anemia of Chronic Disease: References
National Hematologic Diseases Information Service (NHDIS). Anemia of Inflammation and Chronic Disease. US Dept of Health and Human Services, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Disease. 8/2013.
Accessed 4/2014 from http://hematologic.niddk.nih.gov/anemiachronic.aspx.
PubMedHealth. Anemia of Chronic Disease. US Dept of Health and Human Services, National Institutes of Health, National Library of Medicine, National Center for Biotechnology Information. 2/28/2011. Accessed 4/25/2012 from http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001591/.
Impact of anemia on mortality, cognition, and function in community-dwelling elderly. Denny SD; Kuchibhatla MN; Cohen HJ Am J Med. 2006 Apr;119(4):327-34.
Weiss, G, Goodnough, LT. Anemia of chronic disease. N Engl J Med 2005; 352:1011.